LockCrypt will try to open the database from the location set in the Options dialog. To open a different file, specify it as a parameter when launching LockCrypt.exe or LockCrypt.jar. The absolute path to the file must be specified, it is not possible to specify just a filename.
For Example
C:\Program Files\LockCrypt\LockCrypt.exe will start LockCrypt and open the default database or prompt you to create a new one if it doesn't exist.
C:\Program Files\LockCrypt\LockCrypt.exe F:\database.lce will start LockCrypt and open file F:\database.lce, which could be on a portable drive.